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    [b]22nd International Molecular Medicine Tri-Conference


    Organisers: Cambridge Healthtech Institute

    Dates: 15[sup]th[/sup]-20[sup]th[/sup] February 2015

    Location: Moscone North Convention Center, San Francisco CA

    The website gives all the necessary information on abstract submission, fees, registration, conference agenda, hotel, exhibitions and other important facts. The attached document shows the agenda at a glance.

    Purpose of the conference

    The 22nd International Molecular Medicine Tri-Conference is set up to be the industry's Preeminent Event on Molecular Medicine, focusing on Drug Discovery, Genomics, Diagnostics and Information Technology. It includes an expanded program that includes 6 symposia, over 20 short courses, and 17 conference programs.


    On the website can be found details of all the speakers and a detailed agenda. The six main symposia are:

    • New Frontiers in Gene Editing - NEW
    • Circulating Cell-Free DNA
    • Genomics in Medicine
    • Point-of-Care Diagnostics
    • Clinical Cancer Immunotherapy - NEW
    • Genomics & Sequencing Data Integration, Analysis and Visualization


    • Over 3000+ attendees from over 40 countries
    • Over 500 speakers from across all industries, all research fields, and from all over the world
    • Over 400 presentations and panel discussions
    • New 2015 Programs focusing on Genomic Technologies for Patient Stratification and Technology-Driven Oncology Clinical Development
    • Create Your Conference: choose from All Access or build your own program with the a-la-carte option
    • Showcase your Research by Presenting a Scientific Poster
    • Opportunity to participate in one of 40 Roundtable Discussions
    • Book meetings with fellow attendees using Intro-Net
    • View over 150 Scientific Posters
    • Schedule your days' events using the Tri-Conference App
    • Visit with over 200 companies in the exhibit hall
    • Network with your peers during coffee breaks and receptions
    • Attend Sponsored Luncheon Presentations
    • Student Fellowships available for Grad Students and PhD Candidates

    .pdf   2015-MMTC-CAG-Brochure.pdf   (Size: 370.46 KB / Downloads: 0)

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    Variants of two genes named catechol-O-methyltransferase (COMT) and tryptophan hydroxylase 2 (TPH2), associated with dopamine and serotonin regulation respectively, have been linked to increased risk of post-traumatic stress disorder (PTSD) in a new study. The study is published in the February 2015 edition of the Journal of Affective Disorders.

    Senior author Dr. Armen Goenjian, of the Semel Institute for Neuroscience and Human Behavior at UCLA, explains that not everyone experiences PTSD after a traumatic event and that there may be a genetic basis to this difference: "Many people suffer with post-traumatic stress disorder after surviving a life-threatening ordeal like war, rape or a natural disaster. But not everyone who experiences trauma suffers from PTSD. We investigated whether PTSD has genetic underpinnings that make some people more vulnerable to the syndrome than others."

    The study involved 200 Caucasian Armenian adults who were exposed to the 1988 Spitak earthquake. Individuals were from 12 multigenerational (3–5 generations) families. Dr Goenjian travelled to Armenia at the time of the earthquake and helped establish two psychiatric clinics, with support from the Armenian Relief Society. The clinics treated earthquake survivors for 21 years. The participants in the study were recruited from these clinics and donated blood samples for genetic analysis by Dr Goenjian and his colleagues in UCLA. A previous study by the team published in 2012 showed that PTSD was more common among individuals carrying two depression-associated gene variants.

    The current study focused on COMT and TPH-2. COMT is an enzyme involved degradation of the neurotransmitter dopamine, which controls the reward and pleasure centres of the brain and is involved in regulation of mood, thinking, attention and behaviour. Imbalance in dopamine levels is critical in various neurological and psychological disorders. TPH-2 is involved in control of serotonin production. Serotonin is a brain hormone involved in regulation of processes including mood, sleep and alertness, which are affected by PTSD. Selective serotonin reuptake inhibitors are antidepressants which are now being used in other disorders, including PTSD. In the study, the researchers assessed both PTSD and depression using the UCLA PTSD Reaction Index based on DSM-5 criteria, and the Beck Depression Inventory.

    Results of the study indicated that the COMT allele rs4633C and the TPH-2 allele rs11178997T were associated with variance in PTSD severity. Dr Goenjian explains: "We found a significant association between variants of COMT and TPH-2 with PTSD symptoms, suggesting that these genes contribute to the onset and persistence of the disorder. Our results indicate that people who carry these genetic variants may be at higher risk of developing PTSD."
    Key to the study was the use of up-to-date DSM-5 criteria for assessment of PTSD and assessment of genes' role in predisposition to the disorder. Dr Goenjian says: "Assessments of patients based upon the latest diagnostic criteria may boost the field's chances of finding new genetic markers for PTSD. We hope our findings will lead to molecular methods for screening people at risk for this disorder and identify new drug therapies for prevention and treatment."

    However, Dr Goenjian cautions that in common with other psychiatric disorders, this complex disease is likely to be influenced by the effects of multiple genes and that studies should continue to identify further gene candidates. He concludes: "A diagnostic tool based upon PTSD-linked genes would greatly help us in identifying people who are at high risk for developing the disorder. Our findings may also help scientists uncover more refined treatments, such as gene therapy or new drugs that regulate the chemicals associated with PTSD symptoms."


    Goenjian AK et al. Association of COMT and TPH-2 genes with DSM-5 based PTSD symptoms. Journal of Affective Disorders;
    Goenjian AK et al. Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms. Journal of Affective Disorders 140(3): 244-52. doi: 10.1016/j.jad.2012.02.015

    Press release: University of California - Los Angeles Health Sciences; available at

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  • 01/10/15--03:48: Introduction
  • Hello everyone! My name is Revatti. I'm from Pune, India. This forum is amazing and thanks for all the valuable information shared  Smile

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  • 01/12/15--14:52: careers
  • career for M.Sc Animal Biotechnology...?

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  • 01/13/15--04:47: scope of biotechnology
  • hi,
    i have completed my 12  and i just wanted to know that is there is a scope of btech biotechnlogy or bsc biotech
    which is better option for carrer and job option and in which industry there is a scope
    some colleges give btech biotech + mba , is this a good option in terms of job
    and please provide colleges for both of em
    and i also wanted to knw how vast the carrer option it give
    iam really confused  pls rply soon
    heartiest regards

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    Below I summarise some courses available from five highly respected institutions. I also include useful links for those who want to find out more about individual courses or seek out further courses not included here.

    University of Leeds
    The University of Leeds is considered to be one of the top ten UK research universities and offers two MSc programmes with relevance to Biotechnology as follows:
    M.Sc. Plant Science and Biotechnology; Faculty of Biological Sciences, University of Leeds:
    This programme is delivered full-time over one year on campus, in English, and fees are € 10,895 / Year (EEA) or € 22,751 / Year (Non-EEA). The programme begins in September each year.

    Full details for this programme can be found by following these links:
    M.Sc. Biotechnology; Faculty of Biological Sciences, University of Leeds
    This programme is delivered full-time over one year on campus, in English, and fees are € 10,895 / Year (EEA) or € 22,751 / Year (Non-EEA). The programme begins in September each year.
    According to the University this programme “integrates biological sciences with biochemical engineering to provide training for the modern biotechnology industry. In particular, it focuses on the applications of biotechnology in medicine and agriculture.”
    Full details for this programme can be found by following these links:
    University of Essex
    Grad.Dip. Biotechnology with English for Academic Purposes; University of Essex
    This programme is delivered full-time over nine months on campus, in English, and fees are € 5,640 / Year (EEA) or € 11,471 / Year (International). The programme begins in October each year. You are normally required to take an English Proficiency Test such as IELTS.
    According to the University, This Graduate Diploma course is “designed for those who need to improve their language and academic skills, as well as their subject knowledge in biological sciences, before going onto a Masters course. Successful completion of the Graduate Diploma, at the required level, will normally qualify you for entry to an appropriate Masters-level course in our Department of Biological Sciences.”
    Full details of this programme can be found by following this link:
    University of East London
    The University of East London is a relatively new university (designated in 1992) ranked number 201 in the Academic Ranking of World Universities.
    It offers two MSc programmes with relevance to Biotechnology:
    M.Sc. Biotechnology ; University of East London
    This programme is delivered full-time or part-time on campus (full-time duration one year), in English, and fees are € 6,580 / Year (EEA) or € 11,960 / Year (Non-EEA). The programme begins in February or September each year. You are normally required to take an English Proficiency Test such as IELTS.

    Full details of the programme can be found by following these links:
    M.Sc. Biotechnology and Management; University of East London
    This programme is delivered full-time or part-time over one year on campus (full-time duration one year), in English, and fees are € 7,050 / Year (EEA) or € 10,792 / Year (Non-EEA) The programme begins in February or September each year. You are normally required to take an English Proficiency Test such as IELTS.

    Full details of the programme can be found by following these links:
    University of Westminster
    Located in London, this university has one of the largest and most diverse overseas student bodies of any university in the world, from over 150 countries. It has a student body of 400,000 students.
    The University of Westminster offers one MSc programme with relevance to Biotechnology:
    M.Sc. Applied Microbiology and Biotechnology; University of Westminster
    This programme is delivered full-time over one year or part-time over two years on campus, in English, and fees are £ 8,000 / Year (EEA) or £ 12,500 / Year (Non-EEA). The programme begins in September each year. You should have an Honours degree in biological sciences, biotechnology or a related discipline, or an equivalent qualification. If your first language is not English you should have an IELTS score of at least 6.5, with the written component at a minimum of 6.5 (or equivalent). During the induction stage of the course, if you do not have English as your first language, you will need to complete Academic English screening and any resulting recommended Academic English support activity.
    Full details of the programme can be found by following these links:

    The University of Edinburgh
    The University of Edinburgh has 32,591 students of whom 11,607 are international, from over 130 different nationalities. They were ranked first in Scotland and fifth in the UK in the most recent RAE, a UK-wide study of research excellence.
     The University of Edinburgh offers a distance learning MSc option relevant to biotechnology:
    M.Sc. Drug Discovery and Protein Biotechnology (Online Distance Learning) (online study); The University of Edinburgh
    This programme is delivered part-time online over two years and the fees are €6201 per year (EEA and non-EEA). The course begins each year in September. You are normally required to take an English Proficiency Test such as IELTS.
    According to the university, in this programme you will “study the design and potential uses of different families of proteins and will examine the experiences of successful entrepreneurs in the field who have been involved in the commercialisation of biopharmaceuticals. Your research project will focus on the early phases of an industrial biologics design programme…You will enhance your career prospects with marketable analytical and presentation skills.”
    Full details of the programme can be found by following the links:

    These are just examples of some the many excellent programmes available in the UK. For further information check out individual university websites and these useful links:|kw-biotechnology|lv-master

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    I want to create a Useful online BioInformatics tool, to hopefully help you solve a very difficult problem or set of problems. I'm thinking about tools in a more general sense that can help you overcome any challenge you face whether it's technical, biological, mathematical, or anything etc. Anything that takes you lots of time, energy or irritation or is repetitive can be considered a problem or challenge. I want to help you solve your biggest problems.

    What are some of the biggest challenges you face in your day to day work?
    Are there tools or capabilities that you wish existed, but don't?

    thank you for your time,

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    Hello all,
    I am Pushkar Bhojane studying MSc Part 2 in Biotechnology. Can any of you guys suggest me a easy and quick protocol for detecting phosphorous content from soil/compost. We have a protocol which employs use of molybdate reagent and then adding of Stannous chloride. But there is some problem with the protocol. I have tried to search methods for the same. If any you can help please let me know.
    Thank you.

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    Hi Everyone,
    Any advice on what resources or journals to follow to build my subject. I am interested in medical biotechnology but confused to choose between tons of publications. Please Help!!!

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    I have completed my 12th standard and wanted to know that is there is a scope of B.Tech in biotechnology or BSC in biotech.

    Which is a better option for my career and job future job prospects. In which industry there is a scope for me.

    Some colleges give B.Tech biotech + MBA degree, is this a good option in terms of job. Please provide good college names for both of them, and i also wanted to know how vast of a career option does it give.

    I am really confused  please reply soon.

    heartiest regards
    thank you

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    Best Biotech/Life Science Companies to work for (UK)

    There are many large and smaller Biotech/Life Science companies based in the UK who offer opportunities to develop a rewarding career. According to the University of Oxford career service: “There are over 900 pharmaceutically related biotech companies in the UK which employ nearly 26,000 people, although the majority of them have fewer than 50 employees. Many of the UK’s biotech companies originate from universities as ‘spin-outs’ and are located around Oxford, Cambridge and in Scotland.” Below I summarise a few of the available options. I include useful links for those who would like to seek more detailed information. In all cases, qualifications and application processes will vary depending on the company and the specific position. Full instructions and information can be found on the company websites.

    Glaxo Smith Kline (GSK)
    GSK, whose focus is on small Molecules, vaccines and biologics, have a range of opportunities from internships, graduate positions or next career moves for experienced professionals. Their headquarters are in London, but have other UK bases for example in Hounslow and Irvine, and they employ over 99,000 people in 150 countries. Detailed information about all aspects on GSK operations and products can be found on their website: They run programmes including the Future Leaders Programme for graduates which requires for you to be on track for a 2.1 degree or have achieved this already. Recruitment takes place annually from September onwards.
    To find out about current career opportunities with GSK in the UK follow this link:
    Astra Zeneca
    Astra Zeneca, whose focus is on small molecules and biologics, have their main campus in the UK in Cambridge but they also have operations in, for example, London, Edinburgh and Macclesfield. According to their website they currently have 73 positions available in the UK, including for example Senior Principle Scientist in Molecular and Cellular Biology (Cambridge), Team Manager (CPUT team) in Chemical Development (Macclesfield) or VP Regulatory RIA (Cambridge). Qualifications needed vary depending on the position being applied for.
    To find out about current career opportunities with Astra Zeneca in the UK follow this link:
    Astra Zeneca is only one of many options in Cambridge. The city is also home to many smaller “spin-out” Biotech/Life sciences companies, as well as larger multinationals and is at the centre of the Cambridge Biotechnology Cluster. An example of a smaller Cambridge-based company is F-Star, which focuses on novel bispecific antibodies and was named a by FierceBiotech as one of the Fierce 15 winners in 2011 (
    For more information on the Cambridge Biotechnology Cluster and the opportunities it offers, as well as other clusters centred on London, Oxford and Stevenage, visit the Lifestream website:
    SAFC (Sigma Aldrich)
    SAFC, whose focus is on chemicals, services and APIs, is the custom manufacturing and services business unit of Sigma-Aldrich Corporation. It is a top 10 global specialty chemicals and biologics supplier. Full details of their UK operations can be found here:  They have various operations including in Irvine and Manchester. They claim to offer “challenging and rewarding positions across the life science and high technology industry”. To begin the process of applying for opportunities in this company follow this link to the online expression of interest/application forms: Some examples of the types of positions available in the UK can be viewed by following this link:
    Abbvie, whose focus is on diagnostics and devices, is a global biopharmaceutical company with a UK operation in Maidenhead. Full details of their UK operations can be found at:
    To find out about current career opportunities with Abbvie in the UK follow this link:

    Axis Shield
    Axis Shield, whose focus is on in vitro diagnostic tests, is located in Dundee in Scotland. They are an expanding company and recommend contacting their HR department for further information on career opportunities; email A full description of their operations and products can be found on their website:
    Axis Shield are one of a range of companies with career opportunities based in Dundee, that also include for example CXR Biosciences and Cyclacel Pharmaceuticals

    Prosonix is based in Oxford and is an innovative speciality pharmaceutical company developing a portfolio of inhaled respiratory medicines by design. Full details of their operations and products can be found at:
    To find out more about a career at Prosonix, follow this link and you will find relevant contact details:
    Useful links
    The UK Biotech database is a portal that provides information and statistics about Biotech, Pharma and Medtech companies in the UK. It can be accessed by following this link:
    The Lifestream website life sciences recruitment website gives details on the Biotechology Clusters in the UK and details on available opportunities:
    The following link gives a very comprehensive list of many Biotech/Life Sciences companies throughout the UK, with summaries of the areas of main interest and links to their websites:
    The career advice sections of UK university websites are also very useful sources of information, for example the University of Oxford Careers Service has a useful section on pharmaceuticals and biotechnology that can be found here:

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    I want to know the best BSc.Biotech Colleges ranking in India and scope of study in this regard.

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  • 01/20/15--06:54: MS in biotechnology
  • Hii, I have completed my BSc in biotechnology and I am further planning to pursue MS in biotech in US. I wanted to learn about the job opportunities there in this field. Can you please guide me with the job profiles after an MS in biotechnology and is it worth pursuing further MS?

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    conversion of lactic acid and glycolic acid to polylactic acid and polyglycolic acid respectively any help please ????
    can some one describe simple steps for conversion or polymerisation process Confused  Confused  Confused  Confused  Confused  Confused

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    Hey, I'm in high school and I've recently grown interested in biotech. I want to go into this field as a career and I really want to start doing things now. I would like to build my own lab in my bedroom or garage and start doing experiments, but I have very little knowledge in this topic and I have no clue where to start!

    I have zero experience and zero equipment can someone give me some specific things I can do to get started and begin doing experiments please? What would be some good first-time experiments?

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    I am happy to see a forum like this at least after 15 yrs, since i finished, my Graduation in Biotech MKU, i have drifted my career in different directions, to tell you the truth, i have not had any career in particular, I was running family business for 6 years in India, and during that time  I found new interest in IT and i took some courses but  i did not nail any job, everything was half done, i had landed in Toronto during the same time, and i  taught the IT courses  i learned for a short time, however, i have not landed in any IT job, then i was again busy in this part of the world for 6 yrs with the hotel business, but i kept my interest in my sciences, in fact i took DAT and i did quite well, but again of no use, and i wanted to get into Nursing, i thought it should, be smooth, it is different, and i could not clear all the papers in first semester,  the passing grade is 80%, i just had to leave the way it is, and i continued on taking courses in Accounting and IT, Just finished 2 certificate courses in this December from community college, I am planning to  get into job market. Are there any avenues that can utilize my skills.

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    I just started masters in medical biotechnology with a background IT. I have some knowledge in UNIX. How can I use this? Or should I learn Linux or some other technology. I want to supplement my interest in biotechnology with some IT platform. Any technology/ program that would benefit my career in MBT. Would really appreciate your insight.

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  • 02/02/15--00:37: Hot Topics in Biochemistry
  • I need to write about a new topic or an idea to work on in Biochemistry. Any suggestions ??

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    Hi all,

    I'm currently developing a serological dipstick test and I have difficulties in generating robustness in my results. I'm using antibody-HRP as my detection with 4CN as a precipitate but I would like to create a SOP to increase the robustness for my assay. But when i replicate my tests I get quite high variation in the intensities in my spots. Would changing into DAB generate more reproducible results? Is it simply impossible to get a good robustness when using an enzyme reaction to visualise primary antibodies?

    all the best

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    Hello, anyone use yeast extract for your fermentation? Which brand you use currently?

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