New "viral video" captures approach and attachment of viral-like particles to live cells
The study of how viruses or nanoparticles designed to deliver therapuetics function requires knowledge of how a particle approaches and attaches to a cell membrane, enters the cell, and is subsequently trafficked within the cell. Although delivery of viral payloads to cellular machinery have been visualized, the visualization of the approach and attachment of a particle to a cell membrane has remained more elusive.
The study of how viruses or nanoparticles designed to deliver therapuetics function requires knowledge of how a particle approaches and attaches to a cell membrane, enters the cell, and is subsequently trafficked within the cell. Although delivery of viral payloads to cellular machinery have been visualized, the visualization of the approach and attachment of a particle to a cell membrane has remained more elusive.